Acinic cell carcinoma of ascending ramus mandible: a rare case report
Keywords:Acinar cell carcinoma, Mandible, Salivary gland cancer
AbstractAcini cell carcinoma are low grade tumors of the salivary glands with a rare occurrence in the axial or appendicular skeleton. The parotid, submandibular and the minor salivary glands are sites of involvement in that order. Painless swelling is the usual presentation with a lytic appearance on radiology and imaging, CT or MRI, FNAC can to some extent differentiate between a benign or malignant lesion thereby dictating the likely extent of excision. On histopathological examination of resected specimens, acinic cell carcinoma shows tumor cells arranged as papillary clusters, acinar pattern and dispersed population with individual tumor cells displaying moderate nuclear pleomorphism, anisonucleosis, round nuclei and moderate amount of ill-defined granular cytoplasm. A unique intraosseous presentation of acinic cell carcinoma, in an elderly male, necessitated a segmental partial mandibulectomy and a comprehensive neck dissection. The tumour area was widely excised from the second premolar region to the coronoid process, and radical neck dissection was performed.
Bajpai, Manas. Central Acinic Cell Carcinoma of the Mandible Simulating as Benign Odontogenic Lesion: A Case Report. Iranian J Med Sci. 2018;43(2):223.
Godwin JT, Foote FW, Frazell EL. Acinic cell adenocarcinoma of the parotid gland: report of 3 cases and literature review. Revista portuguesa de estomatologia, medicinadentaria e circurgia Maxillofacial. 2010;51:5-11.
Hara I, Ozeki S, Okamura K, Toshitani K, Taniguchi K, Honda T, et al. Central acinic cell carcinoma of the mandible, Case report. J Craniomaxillo Fac Surg. 2003;31:378-82.
Hiremath V, Mishra N, Patil SG. Intraosseous acinic cell carcinoma. Niger J Clin Pract. 2013;16:386.
Nakazawa M, Ohnishi T, Iwai S, Sakuda M. Central acinic cell carcinoma of the mandible. Report of a case. Int J Oral Maxillofac Surg. 1998;27:448-50.
Barnes L, Eveson JW, Reichart P, Sidransky D. World Health Organization Classification of Tummours: Pathology and Genetics of Head and Neck Tumours. Lyon: IARC Press; 2005.
Oliveira LR, Soave DF, Costa JPO, Silva RA. Acinic cell carcinoma of parotid gland: Report of three cases and literature review. Revista Portuguesa de Estomatologia, Medicina Dentaria e Cirurgia Maxilofacial. 2010;51:5-11.