Evaluation of hearing in patients of chronic renal failure

Sabreena Mukhtar, James Thomas, Girija Ghate, Raphella Khan


Background: Chronic kidney disease (CKD) is considered to be a major public health problem and only some studies have subsequently suggested the possibility of a link between the ear and the kidney. The aim of the study was to look for an association between the hearing loss and its association with CKD in absence of any underlying co-morbidities.

Methods: The study design was a hospital based cross sectional study. 50 patients diagnosed with CKD were included. The patients were subjected to general physical examination, examination of ear by otoscopy and hearing test by tuning fork test (256 Hz, 512 Hz and 1024 Hz). Pure tone audiometry (PTA) was also done.  

Results: It was observed that 24% patients were having unilateral or bilateral hearing loss. Of the 12 patients with hearing loss, PTA threshold was below or equal to 35 dB in 4 patients. Hearing threshold of 45 dB was observed in 3 patients. All 3 patients had unilateral involvement. 2 had hearing loss in right ear whereas left ear was involved in 1 patient. 5 patients had hearing threshold between 45-60 dB. Of these 5 patients, 3 had bilateral ear involvement whereas unilateral ear involvement was seen in remaining 2 patients.

Conclusions: CKD is commonly associated with senorineuronal hearing loss. The incidence was 24% in our study population. PTA can be a non-invasive procedure which may be employed to detect CKD patients suffering from any hearing loss.


CKD, Sensorineural hearing loss, PTA, Heamodialysis

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Zeigelboim BS, Mangabeira-Albernaz PL, Fukuda Y. High frequency audiometry and chronic renal failure. Acta Otolaryngol. 2001;121(2):245-8.

Morton LP, Reynolds L, Zent R, Rayner BL. Hearing thresholds in CAPD patients. Adv Perit Dial. 1992;8:150-2.

Hodi C, Thodis E, Danielides V, Pasadakis P, Varge- mezis V. Hearing in renal failure. Nephrol Dial Transplant. 2006;21(11):3023-30.

Alport AC. Hereditary familial congenital haemorrhagic nephritis. Br Med J. 1927;1(3454):504-6.

Vilayur E, Gopinath B, Harris DC, Burlutsky G, McMahon CM, Mitchell P. The association between reduced GFR and hearing loss: a cross-sectional population-based study. Am J Kidney Dis. 2010;56(4):661-9.

Thodi C, Thodis E, Danielides V, Pasadakis P. Varge- mezis V. Hearing in renal failure. Nephrol Dial Transplant. 2006;21(11):3023-30.

Samir M, Riad H, Mahgoub M, Awad Z, Kamal N. Transient otoacoustic emissions in children with chronic renal failure. ClinOtolaryngol Allied Sci. 1998;23(1):87-90.

Gurbanov FA. Hearing status in patients with pronounced chronic kidney insufficiency. Vestn Otorinolaringol. 1999;2:39-41.

Kang SM, Lim HW, Yu H. Idiopathic sudden sensorineural hearing loss in dialysis patients. Ren Fail. 2018;40(1):170-4.

Seo YJ, Ko SB, Ha TH, Gong TH, Bong JP, Park DJ et al. Association of hearing impairment with chronic kidney disease: a cross-sectional study of the Korean general population. BMC Nephrol. 2015;16:154-8.

Govender SM, Govender CD, Matthews G. Cochlear function in patients with chronic kidney disease. S Afr J Commun Disord. 2013;60:44-9.

Lin C, Hsu HT, Lin YS, Weng SF. Increased risk of getting sudden sensorineural hearing loss in patients with chronic kidney disease: a population-based cohort study. Laryngoscope. 2013;123(3):767-73.

Peyvandi A, Roozbahany NA. Hearing loss in chronic renal failure patient undergoing hemodialysis. Indian J Otolaryngol Head Neck Surg. 2013;65(3):537-40.

Mudd PA, Edmunds AL, Glatz FR, Campbell KCM, Rybak LP. Inner Ear, Ototoxicity. Available at: Accessed on 1 September 2019.

Selimoglu E. Aminoglycoside-induced ototoxicity. Curr Pharm Des. 2007;13(1):119-26.

Lopez PS, Silva DP, Martin LC, Montovani JC. Could the type of treatment for chronic kidney disease affect the auditory system?. Braz J Otorhinolaryngol. 2014;80(1):54-9.