Epidemiological profile of oral cancers in Benin
Keywords:Oral cancer, Tongue cancer, Head and neck cancer
Background: The objective of the study was to study the epidemiological profile of malignant tumours of the oral cavity in Benin from January 2009 to 31 December 2014.
Methods: This was a descriptive cross-sectional study that examined cancers of the oral cavity collected in the registers of the 5 anatomy and pathology laboratories in Benin as well as the only hospital in the country that sends its requests for histological examinations abroad.
Results: With a rate of 19.8%, oral cavity cancer was the most frequent cancer localization in the ENT, head and neck sphere in Benin. The most frequent sites of cancers in the oral cavity were the palate (32.2%) followed by the tongue (25.4%) and the inner face of the cheeks (16.9%). The average age of the patients was 53.18±20.60 years with extremes of 1 year and 90 years. The sex ratio was 0.90. Squamous cell carcinoma was the most common histological type with 67.80%.
Conclusions: Cancer of the oral cavity must be a priority for health authorities in Benin. Research must be initiated to determine the factors that contribute to it.
Saman DM. A review of the epidemiology of oral and pharyngeal carcinoma: update. Head Neck Oncol. 2012:4:1.
Petersen PE. Oral cancer prevention and control - the approach of the World Health Organization. Oral Oncol. 2009;45:454-60.
Warnakulasuriya S. Global epidemiology of oral and oropharyngeal cancer. Oral Oncol. 2009;45(4-5):309-16.
Joshi P, Dutta S, Chaturvedi P, Nair S. Head and neck cancers in developing countries. Rambam Maimonides Med J. 2014;5:9.
Khawaja MR, Mazahir S, Majeed A, Malik F, Merchant KA, Maqsood M, et al. Chewing of betel, areca and tobacco: perceptions and knowledge regarding their role in head and neck cancers in an urban squatter settlement in Pakistan. Asian Pac J Cancer Prev. 2006;7(1):95-100.
Conway DI, Petticrew M, Marlborough H, Berthiller J, Hashibe M, Macpherson LM. Socioeconomic inequalities and oral cancer risk: a systematic review and meta-analysis of case-control studies. Int J Cancer. 2008;122(12):2811-9.
Diz P, Meleti M, Diniz-Freitas M, Vescovi P, Warnakulasuriya S, Johnson NW, et al. Oral and pharyngeal cancer in Europe: Incidence, mortality and trends as presented to the Global Oral Cancer Forum. Translational Res Oral Oncol. 2017;2:1-13.
Shield KD, Ferlay J, Jemal A, Sankaranarayanan R, Chaturvedi AK, Bray F, Soerjomataram I. The global incidence of lip, oral cavity, and pharyngeal cancers by subsite in 2012. CA Cancer J Clin. 2017;67(1):51-64.
Botha, PJ, Schoonees A, Pontes CC. Mapping oral cancer research in South Africa. S Afr Dent J. 2018;73(6):384-94.
Hille J, Johnson NW. The burden of oral cancer in sub-Saharan Africa: An estimate as presented to the Global Oral Cancer Forum, March 2016. Translational Res Oral Oncol. 2017;2:1-13.
Parkin DM, Ferlay J, Jemal A, Borok M, Manraj SS, N’da GG, et al. Cancer in Sub-Saharan. Africa. IARC Scientific Publications No. 167 International Agency for Research on Cancer. Lyon, France. 2018.
Conway DI, Purkayastha M, Chestnutt IG. The changing epidemiology of oral cancer: definitions, trends, and risk factors. Br Dent J. 2018;225(9):867-73.
Tapia JL, Goldberg LJ. The challenges of defining oral cancer: Analysis of an ontological approach. Head Neck Pathol. 2011;5:376-84.
de Camargo Cancela M, Voti L, Guerra-Yi M, Chapuis F, Mazuir M, Curado MP. Oral cavity cancer in developed and in developing countries: population-based incidence. Head Neck 2010;32(3):357-67.
Rivera C. Essentials of oral cancer. Int J Clin Exp Pathol. 2015;8(9):11884-94.
Ly M, Ly A, Rodrigues M, Loriot Y, Deberne M, Boudou-Rouquette P, et al. Le cancer en Afrique, un nouveau défi sanitaire. Exemples du Mali et de l'association OncoMali. Bulletin du Cancer 2010;(97)8:965-8.
Gupta N, Gupta R, Acharya AK, Patthi B, Goud V, Reddy S, et al. Changing Trends in oral cancer - a global scenario. Nepal J Epidemiol. 2016;6:613-9.
Faggons CE, Mabedi C, Shores CG, Gopal S. Review: Head and neck squamous cell carcinoma in sub-Saharan Africa. Malawi Medical J. 2015;27(3):79-87.
Gathere S, Mutuma G, Korir A, Musibi A. Head and Neck Cancers four year trend at the Nairobi Cancer Registry. Afr J Health Sci. 2011;19:30-5.
Foma W, Amana B, Pegbessou E, Bissa H, Adam S, Dolou W et al. Upper aero digestive tract cancers: epidemiological and histopathological aspects in Togo. Int J Otorhinolaryngol Head Neck Surg. 2017;3(1):11-6.
Toure S, Sonko L, Diallo B-K, Diop R, Diop A, Diouf R, Diop EM. Profil épidémiologique des cancers de la cavité buccale au sénégal. Revue de Stomatologie et de Chirurgie Maxillo-Faciale. 2005;106(S4):68.
Mourad M, Jetmore T, Jategaonkar AA, Moubayed S, Moshier E, Urken ML. Epidemiological trends of head and neck cancer in the United States: A SEER Population Study. J Oral Maxillofac Surg. 2017;75(12):2562-72.
Shiboski CH, Schmidt BL, Jordan RC. Cancer de la langue et de l'amygdale: tendances à la hausse chez la population américaine âgée de 20 à 44 ans Cancer 2005;103:1843-9.
Hussein AA, Helder MN, de Visscher JG, Leemans CR, Braakhuis BJ, de Vet HCW, et al. Global incidence of oral and oropharynx cancer in patients younger than 45 years versus older patients: A systematic review. Eur J Cancer. 2017;82:115-27.
Ryan WR, Plonowska K. Human papillomavirus in the mouth and throat more widespread than expected? JAMA Otolaryngol Head Neck Surg. 2018;144(6):525-6.
Yakin M, Seo B, Hussaini H, Rich A, Hunter K. Human papillomavirus and oral and oropharyngeal carcinoma: the essentials. Aust Dent J. 2019;64(1):11-8.
Jin-Kyoung OH, Weiderpass E. Infection and Cancer: global distribution and burden of diseases. Annals of Global Health. 2014;80:384-92.
Aboagye E, Agyemang-Yeboah F, Duduyemi BM, Obirikorang C. Human Papillomavirus Detection in Head and Neck Squamous Cell Carcinomas at a Tertiary Hospital in Sub-Saharan Africa. The Scientific World J. 2019:2561530.
Muange P, Chindia M, Njiru W, Dimba E, Mutave R. Oral Squamous Cell Carcinoma: A 6-Month Clinico-Histopathologic Audit in a Kenyan Population. Open J Stomatol. 2014;4:475-83.
Chidzonga MM. Oral malignant neoplasia: a survey of 428 cases in two Zimbabwean hospitals. Oral Oncol. 2005;42(2):177-83.
Scully C, Bagan J. Oral squamous cell carcinoma overview. Oral Oncology 2009;45:301-8.
Markopoulos AK. Current Aspects on Oral Squamous Cell Carcinoma. The Open Dentistry J. 2012;6:126-30.