DOI: http://dx.doi.org/10.18203/issn.2454-5929.ijohns20200153

Drug utilization pattern of antimicrobial agent used in ear, nose and throat outpatient and inpatient department at tertiary care teaching centre

Renu Arora, Sumit Upadhyay, Hukum Singh, Anurag Bajpai

Abstract


Background: The prospective, observational study was designed to assess the prescribing pattern of drug usage in ENT Department in various diseases conditions.

Methods: Medication utilization Form has been designed based on a WHO format. The patient’s details including patient particulars, diagnosis, investigations, drug details and information regarding the indication for prescribing agents. Patient were enrolled those are either gender with age more than 20 years, outpatients and in patients who are treated in ENT department and who are diagnosed as acute and chronic disease. Exclusion criteria were below the age of 20 years, the patients who were not willing to take antimicrobial agents and those were not able to give consent were excluded.  

Results: Total 1021 prescriptions were analysed, 38.5% were males and 61.5% were females, respectively. 319 of patients were diagnosed with ear, 157 with nose and 489 with throat disorders. The most common disease reported was CSOM in 134 patients and least were only one patient with myringitis. The most frequently prescribed antibiotics were β-lactams was commonly prescribed and least were nitroimidazoles. In the concomitant medications, aceclofenac and serratiopeptidase were most commonly prescribed and least were pantoprazole and domperidone.

Conclusions: Prescribing pattern of usage of antibiotics are more compared to other drugs, β Lactams antibiotics are most commonly prescribed antibiotics in various ENT diseases, usage of brand name are higher than the generic name.


Keywords


Antibiotic, Drug utilization, ENT

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References


Sridevi SA, Janagan T, Rathnasamy P, Rajarajeswari R. Drug utilization study in the otorhinolaryngology department in a tertiary care hospital. IJBCP. 2013;2(3):306-10.

Khan FA, Nizamuddin S. Drug Utilization Patterns of Antimicrobial agents in the Outpatient department of ENT in a tertiary care teaching Hospital of North India. JAPHR. 2011;1(2):22-30.

Watkinson JC, Clarke RW. Scott-Brown’s otolaryngology Head and Neck Surgery. Eighth Edition. CRC Press; 2018.

Needham A, Brown M, Freeborn S. Introduction and audit of general practice antibiotic formulary. J R Coll Gen Pract. 1988;38:166-7.

Needham A, Brown M, Freeborn S. Introduction and audit of general practice antibiotic formulary. J R Coll Gen Pract. 1988;38:166-7.

Huovinen P. Magic bullets, lost horizons: the rise and fall of antibiotics. BMJ. 2002;324:176-9.

Przemyslaw K. Patient compliance with antibiotic treatment for respiratory tract infections. J Antimicrob Chemother. 2002;49:897-903.

Atanasova I, Terziivanov D. Investigations on antibiotics in a hospital for a one-year period. Int J Clin Pharm Ther. 1995;33:32-3.

Laporte JR, Porta M, Capella D. Drug utilization studies: A tool for determining the effectiveness of drug use. Br J Clin Pharmacol. 1983;16:301-4.

Ramchandra K, Sanji N, Somashekar HS, Acharya A, Keerthisagar J, Somappa S, et al. Trends in Prescribing antimicrobial in an ENT Outpatients Department of tertiary care Hospital for upper respiratory Tract Infection. Int J Pharmacol Clin Sci. 2012;1:15-8.

Erwin WG. The Definition of Drug Utilization Review: Statement of Issues. Clin Pharmacol Ther. 1991;50(5):596-9.

Truter I. A review of drug utilization studies and methodologies. Jordan J Pharm Sci. 2008;1:91-104.

Khan FA, Nizamuddin S. Drug utilization patterns of Antimicrobial Agents in the Outpatients Department Of ENT in a tertiary care teaching Hospital of North India. JAPHR. 2011;1(2):22-30.

Anon JB. Acute bacterial rhinosinusitis in paediatric medicine: current issues in diagnosis and management. Pediatr Drugs. 2003;5:25-33.

Stille CJ, Andrade SE, Huang SS, Nordin J, Raebel MA, Go AS, et al. Increased use of second-generation macrolide antibiotics for children in nine health plans in the United States. Paediatrics. 2004;114:1206-11.

Ain MR, Shahzad N. Drug utilization pattern of antibacterials used in ear, nose and throat outpatient and inpatient departments of a university hospital at New Delhi, India. J Pharm Bioallied Sci. 2010;2:8-12.

Padwal S, Kulkarni MD, Deshmukh VS, Patil JR, Jadhav SS, Jadhav AD. Drug use pattern in the ear, nose and throat outpatient department of a rural tertiary care teaching hospital. NJPPP. 2015;5(3):212-6.

Mazzaglia G, Greco S, Lando C, Cucinotta G, Caputi AP. Adult acute upper respiratory tract infections in Sicily: pattern of antibiotic drug prescription in primary care. J Antimicrob Chemother. 1998;41:259-66.

Huchon GJ, Gialdronigraqssi G, Elephants P, Manresa F, Schaberg T, Woodhead M. Initial antibiotic therapy for upper respiratory infections. Eur Respir J. 1996;10:1641-5.

Ryan HS. Pattern of drug utilization in acute tonsillitis in a teaching hospital in Nepal. Indian J Otolaryngol Head Neck Surg. 2003;55:176-9.