Epidemiology of head and neck cancer in a tertiary care hospital
DOI:
https://doi.org/10.18203/issn.2454-5929.ijohns20193877Keywords:
Head and neck cancer, Sites, Squamous cell carcinomaAbstract
Background: Head and neck cancer is a deadly disease that has emerged as major health problem. It constitutes one of the commonest cancers in India. Use of smokeless tobacco (pan masala, zarda etc.,) is on the increase in North India and is responsible for the majority of these tumours. The aim of this study is to evaluate demographic profile of patients with squamous cell carcinoma of head and neck cancer and to assess the most common sub-site involved among these patients.
Methods: Histologically confirmed patients with squamous cell carcinoma of head and neck were included in study. Retrospective study from 1st January 2011-31st December 2015 was conducted. Records from OPD based register of ENT Department of Guru Gobind Singh Medical College and Hospital was used. Data was statistically analyzed.
Results: Among 1,052 patients, 74.4% were males and 25.6% were females. The male to female ratio was found out to be 3:1. Tongue was the most common sub-site involved whereas the retromolar trigone was least common site involved.
Conclusions: The squamous cell carcinomas are the most common head and neck cancer. The carcinomas develop in the upper aero digestive tract after exposure to various carcinogens.
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References
N Denaro, Nigro CL, Natoli G, Russi EG, Adamo V, Merlano MC, The Role of p53 and MDM2 in Head and Neck Cancer. ISRN Otolaryngol. 2011:931813.
Munro AJ, Stafford ND-Head and Neck Cancer, In: Price P, Sikora Karol, T Illidge T, eds. Treatment of Cancer. Boca Raton, Florida, US: Hodder Arnold; 2008: 343-345.
Pannone G, Sanguedolce F, de Maria S, Farina E, Rubini C, Serpico R, et al. Cyclooxygenase isozymes in oral squamous cell carcinoma: a real-time RTPCR study with clinic pathological correlations. Int J Immunopathol Pharmacol. 2007;20(2):317-24.
Choi SY, Kahyo H. Effect of cigarette smoking and alcohol consumption in the aetiology of cancer of the oral cavity, pharynx and larynx. Int J Epidemiol. 1991;20:878-85.
Mashberg A, Boffetta P, Winkelman R, Garfinkel L. Tobacco smoking, alcohol drinking, and cancer of the oral cavity and oropharynx among U.S. veterans. Cancer. 1993;72:1369-75.
Menvielle G, Luce D, Goldberg P, Leclerc A. Smoking, alcohol drinking, occupational exposures and social inequalities in hypopharyngeal and laryngeal cancer. Int J Epidemiol. 2004;33:799-806.
Lee CH, Ko YC, Huang HL, Chao YY, Tsai CC, Shieh TY, et al. The precancer risk of betel quid chewing, tobacco use and alcohol consumption in oral leukoplakia and oral submucous fibrosis in southern Taiwan. Br J Cancer. 2003;88(3):366-72.
Bosch FX, Manos MM, Munoz N, Sherman M, Jansen AM, Peto J, et al. Prevalence of human papillomavirus in cervical cancer: a worldwide perspective. International biological study on cervical cancer (IBSCC) Study Group. J Natl Cancer Inst. 1995;87:796-802.
Mehrotra R, Singh M, Gupta RK, Singh M, Kapoor AK. Trends of prevalence and pathological spectrum of head and neck cancers in North India.Indian J Cancer. 2005;42(2):89-93.
Bhattacharjee A, Chakraborty A, Purkaystha P.Prevalence of head and neck cancers in the north east-An institutional study. Indian J Otolaryngol Head Neck Surg. 2006;58(1):15-9.
Gopalakrishnan SN, Kumar P. Epidemiological study on head and neck malignancies- a study of 150 cases. 2013;3(1):2250-359.