Does hearing loss relate to gestational diabetes mellitus?


  • Devanshu Kwatra Department of ENT, Lady Hardinge Medical College and Hospital, Delhi, India
  • Sunil Kumar Department of ENT, Lady Hardinge Medical College and Hospital, Delhi, India
  • Gautam Bir Singh Department of ENT, Lady Hardinge Medical College and Hospital, Delhi, India
  • Ratna Biswas Department of Obstetrics and Gynecology, Lady Hardinge Medical College and Hospital, Delhi, India
  • Prabhakar Upadhyay Department of ENT, Lady Hardinge Medical College and Hospital, Delhi, India



Gestational diabetes mellitus, Hearing, Pregnancy, Hearing loss


Background: This study aims to check if gestational diabetes mellitus leads to changes in hearing.

Methods: A prospective hospital based observational study was performed with total 60 subjects in age group of 18-40 years in the Department of Otolaryngology and Head and Neck Surgery and the Department of Obstetrics and Gynaecology, Lady Hardinge Medical College, New Delhi between November 2016 to March 2018. Subjects were divided in two groups. The first group included 30 pregnant women with diagnosed gestational diabetes mellitus and the second group had 30 pregnant women not having gestational diabetes mellitus. Pure-tone audiometry and impedance audiometry was performed twice in all the subjects, first during the antepartum period and second time during the postpartum period.  

Results: Significant difference was seen between the average of air conduction threshold values at speech frequencies between the two groups during both antepartum and postpartum period.

Conclusions: The alterations in hearing sensitivity in air conduction between the two groups can be attributed to gestational diabetes mellitus.


Addressing the rising prevalence of hearing loss. Geneva: Licence: CC BY-NC-SA 3.0 IGO. World Health Organization; 2018.

Morgan JM, McCaffrey T. Head and neck manifestations of endocrine disease. In: Scott-Brown's Otorhinolaryngology, Head and Neck Surgery. Gleeson M, editor. 7th edition. London: Hodder Arnold. 2008: 401-402.

Maia CA, Campos CA. Diabetes mellitus as etiological factor of hearing loss. Braz J Otorhinolaryngol. 2005;71:208–14.

Taylor IG, Irwin J. Some audiological aspects of diabetes mellitus. J Laryngol Otol. 1978;92(2):99-113.

Nageris B, Hadar T, Feinmesser M, Elidan J. Cochlear histopathologic analysis in diabetic rats. Am J Otol. 1998;19:63-5.

Tay HL, Ray N, Ohri R, Fronntko NJ. Diabetes mellitus and hearing loss. Clin Otolaryngol. 1995;20:130-4.

Jorgensen MB, Buch NH. Studies on inner-ear and cranial nerves in diabetes. Acta Otolaringol (Stockh.). 1961;107:179-82.

Camisasca L. L’esame dell’apparato cochleo-vestibulare nel diabete mellito. G Sci Med. 1950;5:45-9.

American Diabetes Association, Diagnosis and Classification of Diabetes Mellitus. Diabetes Care. 2009;32(1):62-7.

Metzger BE, Coustan DR. Summary and Recommendation of the Fourth International Workshop Conference on Gestational Diabetes Mellitus. Diabetes Care. 1998;21(2):161-7.

Hod M, Merlob P, Friedman S, Schoenfeld A, Ovadia J. Gestational Diabetes Mellitus: A Survey of Perinatal Complications in the 1980s. Diabetes. 1991;40(2):74-8.

Van Assche FA, Aerts L, Holemans K. The Effects of Maternal Diabetes on the offspring. Baillieres Clin Obstet Gynaecol. 1991;5(2):485-92.

Metzger BE, Lowe LP, Dyer AR, Trimble ER, Chaovarindr U, Coustan DR et al. Hyperglycemia and adverse pregnancy outcomes. The HAPO Study Cooperative Research Group. N Engl J Med. 2008;358(19):1991-2002.

Selcuk A, Terzi H, Turkay U, Kale A, Genc S. Does gestational diabetes result in cochlear damage? The J Laryngol Otol. 2014;128:961–5.

Aladag I, Eyibilen A, Güven M, Atis O, Erkokmaz U. Role of oxidative stress in hearing impairment in patients with type two diabetes mellitus. J Laryngol Otol. 2009;123:957–63.

Hong OS, Buss J, Thomas E. Type 2 diabetes and hearing loss. Dis Mon. 2013;59:139–46.

Frisina ST, Mapes F, Kim S, Frisina DR, Frisina RD. Characterization of hearing loss in aged type II diabetics. Hear Res. 2006;211:103–13.

Akinpelu OV, Mujica-Mota M, Daniel SJ. Is type 2 diabetes mellitus associated with alterations in hearing? A systematic review and meta-analysis. Laryngoscope. 2014;124:767-76.

Yueh B, Shapiro N, MacLean CH, Shekelle PG. Screening and Management of Adult Hearing Loss in Primary Care. JAMA. 2003;289(15):1976.

National Diabetes Data Group. Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes. 1979;28:1039-57.

Harner SG. Hearing in adult-onset diabetes mellitus. Otolaryngol Head Neck Surg. 1981;89(2):322-7.

Horikawa C, Kodama S, Tanaka S, Fujihara K, Hirasawa R, Yachi Y, et al. Diabetes and Risk of Hearing Impairment in Adults: A Meta-Analysis. J Clin Endocrinol Metab. 2013;98(1):51–8.






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