DOI: http://dx.doi.org/10.18203/issn.2454-5929.ijohns20192741

Clival chordoma presenting as a parapharyngeal mass: a diagnostic challenge

Prita Pradhan, Rudra Narayan Biswal, Khageswar Rout, Ranjita Panigrahi, Pranati Misra, Urmila Senapati, Jayasree Rath

Abstract


Though the parapharyngeal space is sites of primary involvement by neoplastic process, they can rarely house masses descending from a base of skull tumour. Chordoma is an uncommon tumour of the skull base and sacrococcyx. Originating from the notochordal remnants, they are locally aggressive causing lytic destruction of the adjacent bony structures, particularly in the base of the skull. The use of surgery and adjuvant high-dose proton RT is documented to produce best results. Here we report a diagnostic challenge posed by a chordoma occurring as a parapharyngeal mass in a 68 year old male.


Keywords


Notochordal, Dysphagia, Sphenoid sinus, S100

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References


Li X, Wang Y, Wang F, Li B, Sun S, Yang H. An unusual case of oropharyngeal chordoma: a case report and literature review. Medicine (Baltimore). 2017;96:e8963.

Erazo IS, Galvis CF, Aguirre LE, Iglesias R, Abarca LC. Clival Chondroid Chordoma: a Case Report and Review of the Literature. Cureus. 2018;10:e3381.

Bharti JN, Dey B, Khurana N. Clival chordoma presenting as sphenoid sinus mass. Head Neck Oncol. 2014;6(2):14.

Zhou Y, Hu B, Wu Z, Cheng H, Dai M, Zhang B. Clival chordoma: long-term clinical outcome in a single center. Medicine (Baltimore). 2018;97:e12207.

Kataria SP, Batra A, Singh G, Kumar S, Sen R. Chordoma of skull base presenting as nasopharyngeal mass. J Neurosci Rural Pract. 2013;4:S95-7.

Khurram SA, Biswas D, Fernando M. A Parapharyngeal soft tissue chordoma presenting with synchronous cervical lymph node metastasis: an unusual presentation. Head Neck Pathol. 2016;10:400-4.

Nguyen RP, Salzman KL, Stambuk HE, Ahuja AT, Harnsberger HR. Extraosseous chordoma of the nasopharynx. AJNR Am J Neuroradiol. 2009;30:803-7.

Sajisevi M, Hoang JK, Eapen R, Jang DW. Nasopharyngeal masses arising from embryologic remnants of the clivus: a case series. J Neurol Surg Rep. 2015;76:e253-7.

Sadashiva N, Nandeesh BN, Shukla D, Bhat D, Somanna S, Devi BI. Isolated sphenoid sinus lesions: experience with a few rare pathologies. J Neurosci Rural Pract. 2017;8:107-13.

Cho HY, Lee M, Takei H, Dancer J, Ro JY, Zhai QJ. Immunohistochemical comparison of chordoma with chondrosarcoma, myxopapillary ependymoma, and chordoid meningioma. Appl Immunohistochem Mol Morphol. 2009;17:131-8.

Coppens JR, Ric Harnsberger H, Finn MA, Sharma P, Couldwell WT. Oronasopharyngeal chordomas. Acta Neurochir (Wien). 2009;151:901-7.