A rare case report of pyogenic granuloma of nasopharynx


  • Kholood S. Assiri ORL-HNS Senior registrar Rhinology and skull base surgery fellowship
  • Mohammad S. Al-Ahmari Department of ORL-HNS, Khamis Mushayt General Hospital, Khamis Mushayt,




Pyogenic granuloma, Epistaxis, Nasopharynx


The etiology of pyogenic granuloma (PG) is unclear; it is a reactive tumor-like lesion arising by various stimuli. This study aims to report a rare case of PG of the nasopharynx in a 47 years old Saudi female patient. On October 15th, 2018, a 47-years old Saudi female presented with nasal obstruction for one month. The patient's complaint was associated with on/off epistaxis, headache and allergic symptoms. On examination, she had pedunculated nasopharyngeal lesion. Radiological studies revealed a right nasal cavity mass, a lesion in the nasopharynx without extension to the adjacent structures. Removal of the lesion by nasoscope and cauterization of the base were done. Histopathology revealed vascularized granulation tissue with ulcerated epithelium and fibrinous exudates. Nasopharyngeal pyogenic granuloma is rare. It is one of the differential diagnosis of nasal bleeding.


Kamal R, Puri A, Dahiya P. Oral pyogenic granuloma: various concepts of etiopathogenesis J Oral Maxillofac Pathol. 2012;16(1):79-82.

Limmonthol S, Sayungkul C, Klanrit P. Oral pyogenic granuloma presenting as an atypically large soft tissue mass: a case report. J Oral Maxillofac Surg Med Pathol. 2014;26(2):258-61.

Fortna RR, Junkins-Hopkins JM. A case of lobular capillary hemangioma (pyogenic granuloma), localized to the subcutaneous tissue, and a review of the literature. Am J Dermatopathol. 2007;29:408–11.

Abaalkhail F, Castonguay M, Driman DK, Parfitt J, Marotta P. Lobular capillary hemangioma of the liver. Hepatobiliary Pancreat Dis Int. 2009;8:323–5.

Abe M, Misago N, Tanaka S, Masuoka J, Tabuchi K. Capillary hemangioma of the central nervous system: a comparative study with lobular capillary hemangioma of the skin. Acta Neuropathol. 2005;109:151–8.

Shivaswamy S, Siddiqui N, Jain SA, Koshy A, Tambwekar S, Shankar A. A rare case of generalized pyogenic granuloma: a case report. Quintessence Int. 2011;42:493-9.

Ramirez K, Bruce G, Carpenter W. Pyogenic granuloma: case report in a 9-year- old girl. General Dentistry. 2002;50(3):280-1.

Patrice SJ, Wiss K, Mulliken JB. Pyogenic granuloma (lobular capillary hemangioma): a clinicopathologic study of 178 cases. Pediatr Dermatol. 1991;8:267–76.

Cawson RA, Binnie WH, Speight PM, Barrett AW, Wright JM. Lucas Pathology of Tumors of oral Tissues. 5th edition. Missouri: Mosby; 1998: 252-254.

Fernandes VLG, Pinto NMD, Sanzgiri VB, Khandolkar P, Sukhthankar IR. A rare case report of pyogenic granuloma of tongue. Int J Otolaryngol Head Neck Surg. 2018;7:75-9.

Bhaskar SN, Jacoway JR. Pyogenic granuloma—clinical features, incidence, histology and result of treatment. Report of 142 cases. J Oral Surg, 1996;24:391-8.

Xu Q, Yin X, Sutedjo J, Sun J, Jiang L, Lu L. Lobular capillary hemangioma of the trachea. Arch Iran Med. 2015;18(2):127-9.

Amirchaghmaghi M, Farnaz F, Nooshin M, Mozafari PM. Extragingival pyogenic granuloma: a case report. Cases J. 2008;1:371.

Neville BW, Damm DD, Allen CM, Bouquot JE. Oral and Maxillofacial Pathology. 2nd edition. Philadelphia: Saunders; 2002: 437-495.

Gomes SR, Shakir QJ, Thaker PV, Tavadia JK. Pyogenic granuloma of the gingiva: a misnomer? - a case report and review of literature. J Indian Soc Periodontol. 2013;17:514-9.

Sternberg SS, Antonioli DA, Carter D, Mills SE, Oberman H. Diagnostic Surgical Pathology. 3rd edition. Philadelphia: Lippincot Williams and Wilkins; 1999: 169-174.

Lawoyin JO, Arotiba JT, Dosumu OO. Oral pyogenic granuloma. A review of 38 cases from Ibadan, Nigeria. Brit J Oral Max Surg. 1997;35:185-9.

Svirsky J. Oral pyogenic granuloma. J Indiana Dent Assoc. 2007;86(1):12-4.

Patil K, Mahima VG, Lahari K. Exragingival pyogenic granuloma. Indian J Dent Res. 2006;17:199–202.






Case Reports