DOI: http://dx.doi.org/10.18203/issn.2454-5929.ijohns20190084

Ultrasonographic and fine needle aspiration cytology correlation of thyroid gland lesions: a study of 100 cases

Nehal R. Patel, Alpesh V. Patel, Vaibhav V. Patel, Payal R. Vadher, Manali B. Kakadia

Abstract


Background: Thyroid gland is unique among endocrine organs as it is the largest endocrine gland in the body and the first to develop in the fetal life. There is approximately 4-5% incidence of clinically apparent thyroid lesions in general population. The goal of USG and FNAC diagnosis work up now is to select those patients for surgery who have a high likelihood of harboring malignancy in the nodule. Ultrasonography is the single most valuable imaging modality in the evaluation of the thyroid gland. Indications for thyroid USG include evaluation for palpable thyroid lesion or suspected thyroid enlargement and workup of thyroid lesions discovered incidentally.The present study is undertaken to evaluate the utility of FNAC in preoperative diagnosis of various thyroid lesions and to evaluate the efficacy of in USG and FNAC differentiating between benign and malignant lesions.

Methods: A retrospective clinical study, 100patients, in the age group of equal to or above 18 years, with thyroid swellings, referred to the department of ENT, sent for USG and FNAC at radiology and pathology department during the period from July 2014 to July 2016.  

Results: Out of 100 cases, 6% were malignant, 94% were benign on grey scale ultrasound. Out of 6 malignant cases 2 cases were confirmed malignant by FNAC.

Conclusions: High resolution grey scale ultrasound has emerged as initial imaging modality of choice for the evaluation of patients with thyroid enlargement. Ultrasound can detect solitary nodule, multiple nodules and diffuse thyroid enlargement. It can also differentiate solid and cystic lesions.


Keywords


FNAC, Ultrasonography, Thyroid swelling

Full Text:

PDF

References


Altavilla G, pascale M, Nenci 1.FNAC of thyroid gland disease. Acta cytological. 1990;34:251-6.

Matesa N. FNAC of the thyroid. Acta Clincroat. 2002;41:23-131.

Bouvet M, Fiedldman JI, Gill GN, Dillmann WH Nahum AM, Russak V, et al. surgical management of the thyroid nodule: patient selection based on the results of FNAC. Laryngoscope. 1992;102:1353-6.

Kapur. Solitary thyroid nodule. Indian J Surg. 1999;44:174-9.

Watters AK, Ahiya AT. Role of USG in the management of thyroid nodules. AM J Surg. 1992;162:654-7.

Sheth S. Role of Ultrasonography in thyroid Disease. Otolaryngol Clin N Am. 2010;43:239-55.

Schlumberger MJ, Filetti S, Hay ID. Nontoxic Diffuse and Nodular Goiter and Thyroid Neoplasia. Willium Textbook of Thyroid Surgery. 12th ed. Volume 14. 2012: 443.

Korum N, Ascii C, Yilmazlar T, Duman H, Zorluoglu A, Tuncel E, et al. Total thyroidectomy: changing trends in surgery. International Surgery. 1997;82:417-19.

Mazzaferri EL. Mnagement of a solitary thyroid nodule. New England J Med. 1993;328:553-9.

Vyas CS, Vijayvargiya SC, Porwal S, Gupta R, Swarnkar M. A study of thyroid swelling with clinicopathological parameteres. Int J Biological Med Res. 2013;4(2):3250-2.

Jain S, Nayak R, Totade S, Shukla N. Study of Clinico-Pathological Correlation of Thyroid Swellings. IJMRR. 2014;2(6):554.

Kamal MM, Arjune DG, Kulkarni HR. Comparative Study of Fine Needle Aspiration and Fine Needle Capillary Sampling of Thyroid Lesions. Acta Cytol. 2002;46(1):30-4.

Sekhari T, Sankar JK, Bansal M. Role of different diagnostic modalities in the evaluation of solitary thyroid nodule; experience in tertiary referral centre of North India. IJNM. 2001;16(3):105-8.

Silverman JF, West LR, Larkin EW, Park HK, Finley JL, Swanson MS, et al. The role of Fine needle aspiration Biopsy in the Rapid diagnosis and Management of thyroid Neoplasm. Cancer. 1986;57:1164-70.

Dhanadia A, Shah H, Dave A. Ultrasonographic and FNAC correlation of thyroid lesions. Gujarat Med J. 2014;69(1):76.

Borah KK, Medhi G, Sarma A. Thyroid Swelling –Evaluation by Ultrasonography with FNAC correlations. J Med Sci Clin Res. 2016;4:10089-99.

Lokhande RB, Gedam BS, Shah Y, Kale V. The accuracy of ultrasonography and fine needle aspiration cytology in the diagnosis of nodular goitre: A prospective analysis of 42 cases. Int J Biomed Adv Res. 2015;6(01):43-6.