Unusual case of a midline neck swelling in a fifty year old female


  • Akshay Agarwal Department of Pathology, MGM Medical College, Navi Mumbai, India
  • Shilpi Sahu Department of Pathology, MGM Medical College, Navi Mumbai, India
  • Reeta Dhar Department of Pathology, MGM Medical College, Navi Mumbai, India




Poorly differentiated carcinoma, Thyroid, Rhabdoid, Azzopardi phenomenon


Goitrous enlargement of the thyroid can present as a massive enlargement of the neck. It can be so huge as to obscure detection of an underlying malignancy. Poorly differentiated carcinoma of the thyroid gland is very rare. A 50 year old female patient who was diagnosed preoperatively as having colloid goiter underwent near total thyroidectomy was diagnosed with poorly differentiated thyroid carcinoma on histopathological examination. This case report highlights the various architectural patterns, azzopardi phenomenon with emphasis on immunohistochemical stains and an aberrant rhabdoid phenotype of tumor cells along with review of literature.


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