Diffuse large B-cell non-hodgkin lymphoma of the ear with intracranial invasion

Alberto Guakil-Haber, Erasmo González-Arciniega, Benjamin García-Enríquez, María Y. Olvera-Suarez, Enrique Segovia-Forero, Raymundo Munguía-Vázquez


We report a 62-year-old woman with primary diffuse large B-cell lymphoma (DLBCL) of the ear. The patient presented with facial palsy, left ear hearing loss and a mass in the left external auditory canal. CT and MRI showed an occupied external auditory canal, middle ear and temporal bone with extensive intracranial invasion, R-CHOP therapy was started, but she died after one course. Primary lymphoma of the ear is extremely rare and to the best of our knowledge this is the first case reported in a Mexican medical center, and also the first overall with such an extensive invasion.


Primary lymphoma, Temporal bone, Ear, External auditory canal, Diffuse large B-cell lymphoma, Intracranial invasion

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