Our experience of clinico-pathological study of thyroid swelling

Authors

  • Vilas R. Kirdak Department of Otorhinolaryngology, JIIUS IIMSR, Warudi Tq., Badnapur Dist., Jalna, Maharashtra, India
  • Sambhaji G. Chintale Department of Otorhinolaryngology, JIIUS IIMSR, Warudi Tq., Badnapur Dist., Jalna, Maharashtra, India
  • Sonali P. Jatale Department of Otorhinolaryngology, JIIUS IIMSR, Warudi Tq., Badnapur Dist., Jalna, Maharashtra, India
  • Kaleem A. Shaikh Department of Otorhinolaryngology, JIIUS IIMSR, Warudi Tq., Badnapur Dist., Jalna, Maharashtra, India

DOI:

https://doi.org/10.18203/issn.2454-5929.ijohns20183396

Keywords:

Thyroid swelling, Goiter, Cytology, Histopathology, Sonography

Abstract

Background: Diseases of thyroid gland are extremely common. Majority of palpable thyroid swellings are asymptomatic occurs in 5% of the population. The main objective of present study is to know the accuracy of FNAC in preoperative diagnosis of clinically palpable thyroid swelling and evaluate the efficiency of FNAC, USG, and TFT in differentiating between benign and malignant thyroid swelling and their confirmation by histopathological reports after operation.

Methods: This prospective study is carried out in 120 cases of thyroid swelling attending to the ENT opd at our hospital. Pearson chi square test used as statistical tool to analyse the data. All patients informed written consent taken. The patients are subjected to detailed history with thorough clinical examination, pathological and radiological investigation. FNAC, USG and TFT were done in each case. The result of FNAC was interpreted.  

Results: The present study includes 120 cases. All patient examined clinically, pathologically and radiological. The common age group of presentation of thyroid swelling is between second to fourth decade. Youngest patient is of 15 yrs. old and oldest is being 68 yrs of age. All 120 cases were evaluated preoperatively and provisional diagnosis was made on the basis of FNAC, TFT and USG. 111 Cases were operated out of total 120 cases. So, the overall accuracy of FNAC in comparisons to HPR is 99.15% with no false positive reports.

Conclusions: The overall incidence of the malignancy in thyroid swelling varies from 10% to 30% according to various studies, in our study the overall incidence of malignancy in thyroid swelling was 5.8%. High index of suspicion should be kept in mind during physical examination for detection of malignancy. FNAC should be done in all cases preoperatively FNAC is safe procedure and cost effective.

 

Author Biographies

Vilas R. Kirdak, Department of Otorhinolaryngology, JIIUS IIMSR, Warudi Tq., Badnapur Dist., Jalna, Maharashtra, India

Ent deprtmnt

Sonali P. Jatale, Department of Otorhinolaryngology, JIIUS IIMSR, Warudi Tq., Badnapur Dist., Jalna, Maharashtra, India

ent

References

Lawrence W Jr, Kaplan BJ. Diagnosis and management of patient with thyroid nodules. J Surg Oncol. 2002;80:157-70.

Quadbeck B, Pruellage J, Roggenbuck U, Janssen OE, Mann K, etal. Long term follow of thyroid nodule growth. Exp Clin Endocrinol. 2002;110:348-54.

Miller JM. Evaluation of thyroid nodule. Med Clinic of North Am. 1985;69:1063.

Ananthakrishnan N, Madhava Rao M, Narasimhan R, Veliath AJ. The single thyroid nodule.503 pts. Indian Journal of Surgery. 1993;55(10):487-92.

Fenn AS. Solitary nodule of thyroid. Ind J Surg. 1980;42:175-1.

Psarras, Papadopaoulous SN, Livadas D, Koutras DA. Single thyroid nodule. Br Surg 1972;59:545-8.

Bhansali SK. Solitary thyroid nodule 600 cases. Ind J Surg. 1982;44:547-61.

Kapur MM, Sarin R, Karmarkar MG, Sarda AK, Solitary thyroid nodule. Indian J Surg. 1982;44:174-9.

Messaries G, Kyriakou K, Vasilopolous P, Tountas C. Single thyroid nodule & C A BMJ Surg. 1974;61:943-4.

Lindsay S, Dailey ME, Friedlander J, Yee G, Soley MH. Chronic thyroiditis. Clinical and pathological study of 354 patient’s J Clin Endocrinol Metab. 1952;12:1578-600.

Hamburger JI, Hamburger SW. Fine needle biopsy of thyroid nodules. N Y State J Med. 1986;86:241-9.

Till AS. Types of carcinoma of thyroid and their presentation. Br J Surg. 1965;52(10):734-5.

Anne McCall. Harriet J, et al. Incidence of thyroid CA in cold nodule and MNG. S Surg. 1986;100(6):112-32.

Vittal S, Kumar KB, Chandrashekaran M, Suchitra V, Jeevarathinam R. Thyroid Surgery. Indian J Surg. 1993;22(4):53-6.

Crile GJr. Treatment of thyroid cyst by aspiration. Surgery. 1966;59:210-1.

Khalid AN, Hollenbeak CS, Quraishi SA, Fan CY, Stack BC Jr. Cost effectiveness of iodine 131 scientighraphy The Ultrasonoghraphy and Fine Needle Aspiration Biopsy in the Initial Diagnosis Of Solitary Thyroid nodule. Arch Otolaryngol Head Neck Surg. 2006;132:244-50.

Burch HB. Evaluation of and management of the solid thyroid nodule. Endocrinol Metab Clin North Am. 1995;24:663-710.

Castro MR, Gharib H. Thyroid fine needle aspiration biopsy. Endocr Pract. 2003;9:128-36.

Cochand-Priollet B, Guillausseeu PJ, Chagnon S, Hoang C, Guillausseau-Scholer C, Chanson P, et al. The diagnostic value of fine needle aspiration biopsy under ultrasonography in non-functional thyroid nodule; A prospective study comparing cytologic and histologic findings. AM J Med. 1994;97:152-157

Kim H. Historical aspect and anatomy of thyroid 14th ed. 1993:556-557.

Nagori, Algotar MJ. Solitary thyroid nodule 100 cases. Ind J Surg. 1992;54(2):75-8.

Alta Villa G, Pascal M, Nenci I. Fine needle aspiration cytology of thyroid gland disease. Act Cytology. 1990;34(2)251-6.

Bouvet M, Feldman JI, Gill GN, Dillmann WH, Nahum AM, Russack V, et al. Surgical management of the thyroid nodule: patient selection based on the results of fine-needle aspiration cytology. Laryngoscope. 1992;102(12):1353-6.

Sonkhya N, Kaur K, Bapna AS, Mital P. A comparative study of fine needle aspiration cytology, ultrasonography and radio nucleotide scan in the management of solitary thyroid nodule. a prospective analysis of fifty cases. Indian J Otolaryngol Head Neck Surg. 2002;54(2):96-101.

Mondal A, Sadhukhan B, Roychaudhuri BK, Banerjee S. Cytodiagnostic accuracy of fine needle aspiration biopsy of cold nodule of thyroid. Indian J of Otolaryngol Head Neck Surg. 1992;2:63-5.

Katz JF, Kane R. A Thyroid nodule: sonographic pathologic correlation. Radiology. 1984;151:741-5.

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Published

2018-08-25

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