Clinico-pathological spectrum of sinonasal masses: a tertiary care hospital experience

Authors

  • Abhishek Maheshwari Department of ENT, Subharti Medical College, Meerut, Uttar Pradesh
  • Anshul Bansal Department of ENT, Subharti Medical College, Meerut, Uttar Pradesh

DOI:

https://doi.org/10.18203/issn.2454-5929.ijohns20174324

Keywords:

Sinonasal masses, Polyp, Nasal obstruction, Squamous cell carcinoma

Abstract

Background: Sinonasal masses (SNM) are a fairly common clinical entity that occurs amongst patients of all age groups. There symptoms and signs frequently overlap, hence a diagnostic dilemma exists. A correct diagnosis is prudent for instituting correct treatment and expecting recovery. The purpose of this retrospective analysis was to decipher and study the various pathologies that present as sinonasal masses.

Methods: A retrospective analysis done on 80 patients of SNM who presented to the Department of ENT, Subharti Medical College and Hospital, Meerut from May 2016 to April 2017. Their biodata, clinical profile and histolopathological diagnosis were analyzed.  

Results: SNM were male predominant and were non-neoplastic in 53 cases (66.25%). Nasal obstruction was the most common presenting feature (71 cases, 88.75%). Nasal polyps are the most commonly encountered SNM. Non-neoplastic SNM were common in the age group of 11 to 40 years. Benign SNM were common during the 2nd to 4th decade of life, while malignant SNM were common from 5th decade onwards.

Conclusions: SNM constitute a very wide spectrum of differential diagnoses. They have a male predominance and majority are non-neoplastic. Nasal polyps are the most commonly encountered SNM, seen during 2nd to 4th decade of life, while squamous cell carcinoma is the most commonly encounterd malignancy, generally from 5th decade onwards. Surgery is the treatment of choice.

References

Zafar U, Khan N, Afroz N, Hasan SA. Clinicopathological study of non‑neoplastic lesions of nasal cavity and paranasal sinuses. Indian J Pathol Microbiol. 2008;51:26‑9.

Somani S, Kamble P, Khadkear S. Mischievous presentation of nasal masses in rural areas. Asian J Ear Nose Throat. 2004;2:9‑17.

Harley EH. Pediatric congenital nasal masses. Ear Nose Throat J. 1991;70:28-32.

Valencia MP, Castillo M. Congenital and acquired lesions of the nasal septum: a practical guide for differential diagnosis. Radio Graphics. 2008;28:205-23.

Kristensen S, Vorre P, Elbrønd O, Søgaard H. Nasal Schneiderian papillomas: a study of 83 cases. Clin Otolaryngol Allied Sci. 1985;10(3):125-34.

Bist SS, Varshney S, Baunthiyal V, Bhagat S, Kusum A. Clinico-pathological profile of sinonasal masses: An experience in tertiary care hospital of Uttarakhand. Natl J Maxillofac Surg. 2012;3:180-6.

Lathi A, Syed MMA, Kalakoti P, Qutub D, Kishve SP. Clinico-pathological profile of sinonasal masses: a study from a tertiary care hospital of India. Acta Otorhinolaryngol Ital. 2011;31(6):372-7.

Rosai J. Rosai and Ackerman’s surgical pathology. 9th ed. New York: Mosby; 2004: 305–334.

Walike JW. Anatomy of the nasal cavities. Otolaryngol Clin North Am. 1973;6:609–21.

Bakari A, Afolabi OA, Adoga AA, et al. Clinico-pathological profile of sinonasal masses: an experience in national ear care center Kaduna, Nigeria. BMC Research Notes. 2010;3:186.

Patel SV, Katakwar BP. Clincopathological study of benign and malignant lesions of nasal cavity, paranasal sinuses and nasopharynx: A prospective study. Orissa J Otolaryngol Head Neck Surg. 2009;3:11‑5.

Humayun AH, Huq AH, Ahmed SM, Khin KU, Bhattacharjee N. Clinicopathological study of sinonasal masses. Bangladesh J Otorhinolaryngol. 2010;16:15‑22.

Thomas JJ, Prasad B, Modwal A, Saboo R, Jain A. Clinicopathological study of masses in sinonasal cavity and nasopharynx. Indian J Basic Applied Med Res. 2016;6(1):724-9.

Mane PS, Agale SV. Clinicopathological Study of Sinonasal Masses. Annals Pathol Laboratory Med. 2017;4(3):261-7.

Casale M, Pappacena M, Potena M, et al. Nasal polyposis: from pathogenesis to treatment, an update. Inflamm Allergy Drug Targets. 2011;10:158-63.

Webb CG, Porter G, Sissons GRJ. Cavernous hemangioma of the nasal bones: an alternative management option. J Laryngol Otol. 2000;114:287-9.

Archontaki M, Stamou AK, Hajiioannou JK, Kalomenopoulou M, Korkolis DP, Kyrmizakis DE. Cavernous haemangioma of the left nasal cavity. Acta Otorhinolaryngol Ital. 2008;28:309-11.

Zimmer LA, Carrau RL. Neoplasms of the nose and paranasal sinuses. In: Bailey BJ, Johnson JT, Newland SD, editors. Head & Neck Surgery - Otolaryngology. 4th ed. Philadelphia, PA: Lippincott, Williams & Wilkins; 2006.

Fasunla AJ, Lasisi AO. Sinonasal malignancies: a 10-year review in a tertiary health institution. J Natl Med Assoc. 2007;99:1407-10.

Weymuller EA, Gal TJ. Neoplasms of the nasal cavity. In: Cummings CW, Flint PW, Harker LA, et al. editors. 4th ed. Mosby; 2005.

Pradhananga RB, Adhikari P, Thapa NM, et al. Overview of nasal masses. J Inst Med. 2008;30:13-6.

Svane-Knudsen V, Jørgensen KE, Hansen O, Lindgren A, Marker P. Cancer of the nasal cavity and paranasal sinuses: a series of 115 patients. Rhinology. 1998;36:12-4.

Resto VA, Deschler DG. Sinonasal malignancies. Otolaryngol Clin North Am. 2004;37:473-87.

Downloads

Published

2017-09-22

Issue

Section

Original Research Articles